Kuan-Hung Chen Selected Research

Therapeutics

10/2023	Macrophage-Hitchhiked Orally Administered β-Glucans-Functionalized Nanoparticles as "Precision-Guided Stealth Missiles" for Targeted Pancreatic Cancer Therapy.
1/2023	Addition of adipose tissue-derived mesenchymal stem cells improves empagliflozin therapy for alleviating hyperglycemia--induced neuropathy.
10/2022	Synergic Effect of Early Administration of Probiotics and Adipose-Derived Mesenchymal Stem Cells on Alleviating Inflammation-Induced Chronic Neuropathic Pain in Rodents.
1/2022	Synergic Effect of Combined Therapy of Hyperbaric Oxygen and Adipose-Derived Mesenchymal Stem Cells on Improving Locomotor Recovery After Acute Traumatic Spinal Cord Injury in Rat Mainly Through Downregulating Inflammatory and Cell-Stress Signalings.
1/2022	Ultrasound-Activated, Tumor-Specific In Situ Synthesis of a Chemotherapeutic Agent Using ZIF-8 Nanoreactors for Precision Cancer Therapy.
10/2021	Combined high energy of extracorporeal shock wave and 5-FU effectively suppressed the proliferation and growth of tongue squamous cell carcinoma.
1/2021	Overexpression of miR-19a and miR-20a in iPS-MSCs preserves renal function of chronic kidney disease with acute ischaemia-reperfusion injury in rat.
10/2020	Circulatory Rejuvenated EPCs Derived from PAOD Patients Treated by CD34+ Cells and Hyperbaric Oxygen Therapy Salvaged the Nude Mouse Limb against Critical Ischemia.
1/2020	Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Effectively Protected the Brain Architecture and Neurological Function in Rat After Acute Traumatic Brain Injury.
1/2020	Melatonin against acute ischaemic stroke dependently via suppressing both inflammatory and oxidative stress downstream signallings.

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Kuan-Hung Chen Research Topics

Disease

38	Inflammation (Inflammations) 10/2022 - 05/2013
18	Ischemia 04/2021 - 11/2015
16	Fibrosis (Cirrhosis) 01/2023 - 08/2014
11	Reperfusion Injury 04/2021 - 11/2015
10	Shock 10/2021 - 01/2015
8	Pain (Aches) 01/2023 - 02/2008
8	Chronic Renal Insufficiency 02/2022 - 01/2017
7	Brain Infarction 04/2021 - 11/2016
7	Ischemic Stroke 02/2020 - 02/2016
6	Brain Edema (Cerebral Edema) 01/2022 - 02/2016
5	Neoplasms (Cancer) 10/2023 - 01/2019
5	Neuralgia (Stump Neuralgia) 10/2022 - 02/2008
5	Chronic Limb-Threatening Ischemia 10/2020 - 09/2018
5	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2019 - 01/2017
5	Hyperalgesia 05/2014 - 05/2010
4	Myocardial Infarction 10/2019 - 01/2017
4	Infarction (Infarctions) 10/2019 - 01/2018
4	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2018 - 11/2016
3	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2019 - 11/2016
3	Cardio-Renal Syndrome 01/2019 - 11/2016
3	Brain Death (Brain Dead) 01/2019 - 12/2017
3	Lung Injury 01/2018 - 11/2016
3	Hypoxia (Hypoxemia) 01/2018 - 02/2016
3	Sepsis (Septicemia) 10/2017 - 11/2016
2	Infections 01/2024 - 02/2014
2	Diabetic Neuropathies (Diabetic Neuropathy) 01/2023 - 01/2015
2	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2022 - 01/2019
2	Peripheral Arterial Occlusive Disease 1 10/2020 - 12/2018
2	Heart Failure 01/2019 - 01/2019
2	Atherosclerosis 01/2019 - 01/2017
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2018 - 01/2017
2	Organophosphate Poisoning 12/2015 - 11/2015
2	Hypersensitivity (Allergy) 01/2014 - 05/2013
1	Heart Diseases (Heart Disease) 01/2024
1	Pancreatic Neoplasms (Pancreatic Cancer) 10/2023
1	Neoplasm Metastasis (Metastasis) 10/2023

Drug/Important Bio-Agent (IBA)

37	Proteins (Proteins, Gene)FDA Link 01/2024 - 02/2008
29	Biomarkers (Surrogate Marker)IBA 01/2023 - 11/2015
18	Caspase 3 (Caspase-3)IBA 10/2022 - 01/2015
15	Matrix Metalloproteinases (MMPs)IBA 10/2023 - 02/2016
15	MelatoninIBA 02/2022 - 11/2015
12	salicylhydroxamic acid (SHAM)IBA 01/2020 - 01/2014
10	Therapeutic UsesIBA 10/2022 - 08/2016
10	Oxygen (Dioxygen)IBA 01/2022 - 02/2016
10	CollagenIBA 01/2019 - 01/2017
8	CreatinineIBA 02/2022 - 08/2016
7	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 01/2017
7	Cytochromes c (Cytochrome c)IBA 10/2020 - 01/2017
7	Exenatide (Byetta)FDA Link 11/2017 - 11/2015
6	NPHS2 proteinIBA 12/2019 - 08/2016
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020 - 08/2014
4	Rosuvastatin Calcium (Crestor)FDA Link 01/2019 - 01/2017
4	LipopolysaccharidesIBA 09/2018 - 11/2016
3	Voltage-Gated Sodium ChannelsIBA 01/2023 - 04/2019
3	Valsartan (Vals)FDA Link 02/2022 - 01/2017
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2021 - 06/2015
3	Coloring Agents (Dyes)IBA 04/2021 - 01/2017
3	HMGB1 Protein (HMG1)IBA 01/2021 - 01/2018
3	prednylidene (Pred)IBA 12/2019 - 11/2016
3	erucylphosphocholineIBA 10/2019 - 01/2019
3	CholesterolIBA 01/2019 - 01/2017
3	InterleukinsIBA 01/2019 - 11/2016
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 11/2016
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 11/2016
3	Propylthiouracil FDA Link 01/2019 - 01/2017
3	Vitamin K 3 (Menadione)FDA Link 09/2018 - 01/2015
3	Cadherins (E-Cadherin)IBA 01/2018 - 08/2016
3	Chemokine CCL5IBA 01/2017 - 02/2016
3	AntioxidantsIBA 01/2017 - 01/2015
3	Freund's AdjuvantIBA 01/2017 - 05/2013
2	Messenger RNA (mRNA)IBA 01/2024 - 01/2015
2	VaccinesIBA 01/2024 - 12/2021
2	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2019
2	empagliflozinIBA 01/2023 - 01/2019
2	Mitogen-Activated Protein KinasesIBA 01/2022 - 12/2019
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 04/2021 - 01/2017
2	TNF Receptor-Associated Factor 6 (TRAF6)IBA 01/2021 - 12/2019
2	MicroRNAs (MicroRNA)IBA 10/2020 - 01/2017
2	2',7'-dichlorodihydrofluorescein diacetateIBA 01/2020 - 01/2020
2	Histones (Histone)IBA 01/2020 - 01/2017
2	Aquaporin 4IBA 01/2020 - 11/2016
2	Erythropoietin FDA Link 10/2019 - 01/2017
2	Connexin 43 (Connexin43)IBA 01/2019 - 11/2016
2	Fibronectins (Fibronectin)IBA 01/2019 - 01/2018
2	Mitochondrial DNA (mtDNA)IBA 01/2019 - 01/2018
2	Sirtuin 1IBA 09/2018 - 01/2017
2	Sirtuin 3IBA 09/2018 - 01/2017
2	Glial Fibrillary Acidic ProteinIBA 01/2017 - 11/2016
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 11/2016 - 11/2016
1	Immune Checkpoint InhibitorsIBA 10/2023
1	GlucansIBA 10/2023

Therapy/Procedure

45	Therapeutics 10/2023 - 08/2014
8	Ligation 01/2019 - 02/2016
4	Nephrectomy 03/2019 - 01/2017
4	Punctures 01/2019 - 01/2017
3	Extracorporeal Shockwave Therapy 01/2019 - 01/2015
2	Hyperbaric Oxygenation 10/2020 - 12/2018
2	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2018 - 03/2017
2	Axotomy 01/2014 - 05/2010
1	Cerebrospinal Fluid Shunts 01/2023